Liver Dysfunction

blog post

Type of Disease
Description
Examples of Causes/Conditions
Acute liver failure
Rapid decrease in liver function
Drugs, toxins, a variety of liver diseases
Autoimmune-associated
The body produces an inappropriate immune response against itself; sometimes develops antibodies against own liver tissue
PBC (Primary biliary cirrhosis), PSC (Primary sclerosing cholangitis), Autoimmune hepatitis
Budd-Chiari syndrome
Blood clots impede blood flow from the liver; symptoms such as ascites, enlarged liver, jaundice, and abdominal pain can develop
Hypercoagulable disorders, liver injury, cancer,parasitic infection
Cirrhosis
Scarring of liver tissue leads to decreased liver function
Can be caused by a variety of conditions but usually a result of chronic hepatitis, alcoholism, or chronic bile duct obstruction
Genetic
Gene mutations can lead to liver damage, disease; relatively rare conditions
Hemochromatosis, Alpha-1 antitrypsin deficiency, Wilson's disease
Hepatitis
Acute or chronic liver inflammation
Viruses, alcohol abuse, drugs, toxins, autoimmune, nonalcoholic fatty liver disease (NAFLD)
Infections
Certain infections can cause various degrees of liver damage, blockage of bile ducts
Viral hepatitis, Parasitic infection
Liver cancer
A cancer that originates in the liver
Increased risk with cirrhosis and chronic hepatitis; hepatocellular carcinoma (HCC) is most common primary liver tumor
Obstruction of bile ducts
Complete or partial blockage of bile ducts
Tumors, gallstones, inflammation, trauma