Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis.

COMPLICATIONS OF CHRONIC LIVER DISEASE

• Portal Hypertension
  • Ascites
  • Hypersplenism (with or without splenomegaly)
  • Lower oesophageal varices and rectal varices

• Synthetic Dysfunction
  • Hypoalbuminaemia
  • Coagulopathy

• Hepatopulmonary Syndrome

• Hepatorenal Syndrome

• Encephalopathy

• Hepatocellular Carcinoma (also called hepatoma)